The possibility that Alzheimer’s disease diagnosis is associated with viruses, bacteria, fungi, and parasites has been postulated over the past three decades. By BEN EDIDIN JANUARY 20, 2025 11:23 (L-R) In green – herpes virus proteins. In red – Alzheimer’s tau. In orange – a merge of the two. (photo credit: Shemesh Lab) Researchers from the School of Pharmacy at the Hebrew University of Jerusalem have discovered a surprising correlation between Alzheimer’s disease and the presence of Herpes Simplex Virus-1 (HSV-1). Their study, “Anti-Herpetic Tau Preserves Neurons vis the cGAS-STING-TBK1 Pathway in Alzheimer’s Disease,” was published in the peer-reviewed journal Cell Reports in early January. Alzheimer’s disease diagnosis depends on Neurofibrillary tangles, which are made predominantly of the proteins, extracellular β-amyloid (Aβ), and intracellular hyperphosphorylated tau (p-tau). The causes of these pathologies remained